Takeda Pharmaceutical, a global, research and development-driven pharmaceutical company, has announced that the company will feature new clinical analyses and outcomes research during three upcoming medical meetings: the 53rd Annual Meeting of the American Society of Clinical Oncology (ASCO), June 2-6 in Chicago, the 22nd Congress of the European Hematology Association (EHA), June 22-25 in Madrid, and the International Conference on Malignant Lymphoma 2017 (ICML), June 14-17 in Lugano, Switzerland. Presentations at this year’s meetings will highlight Takeda’s ongoing commitment to patients with hematologic cancers, while demonstrating a broadened portfolio with the recent addition of new targeted therapies and pipeline assets in solid tumors.
“Takeda Oncology’s presence at these upcoming medical meetings demonstrates our relentless pursuit to deliver innovations for patients with cancer,” said Christophe Bianchi, M.D., president, Takeda Oncology. “The data we are presenting highlight the depth and breadth of our recently expanded portfolio, now including both hematological malignancies and solid tumors with the recent approval of Alunbrig (brigatinib) for metastatic non-small cell lung cancer, and brings us one step closer to our aspiration to cure cancer.”
At ASCO, Takeda will present patient-reported outcomes and quality of life findings from the pivotal Phase 2 ALTA (ALK in Lung Cancer Trial of AP26113) trial of Alunbrig, which recently received Accelerated Approval from the U.S. Food and Drug Administration for the treatment of patients with anaplastic lymphoma kinase-positive (ALK+) metastatic non-small cell lung cancer (NSCLC) who have progressed on or are intolerant to crizotinib. Approximately two to eight percent of patients with metastatic NSCLC have a rearrangement in the ALK gene. Results from an analysis of the drug’s activity in crizotinib-resistant ALK+ NSCLC patients according to ALK plasma mutation status will also be featured.
Both ASCO and EHA will feature findings from studies of Takeda medicines for the treatment of a variety of blood cancers, including lymphoma, multiple myeloma and chronic myeloid leukemia. Data from the Phase 3 Alcanza study of Adcetris (brentuximab vedotin) in CD30-positive cutaneous T-cell lymphoma will be presented at both ASCO and EHA. Several phase 1 and 2 studies investigating Ninlaro (ixazomib) in patients with newly diagnosed multiple myeloma will be presented at EHA, including two oral presentations which evaluated ixazomib plus lenalidomide and dexamethasone followed by maintenance with single-agent ixazomib. In addition, ASCO and EHA will highlight five-year data from the Phase 2 PACE trial of Iclusig (ponatinib) in heavily pretreated chronic phase chronic myeloid leukemia.