Council of Scientific and Industrial Research (CSIR) scientists have secured US Patent for a method to treat Type 2 diabetes using adipocyte insulin. The patent (No: 7,129,211) was granted on October 31, 2006 on an application filed three years ago.
The invention relates to an adipocyte Insulin adpInsl with Insulin A and B chains of SEQ ID Nos. 1 and 2 and an effective method of treating type 2 diabetes in a subject using adipocyte insulin, said method comprising steps of administering the insulin to a diabetic intraperitoneally.
A process of isolating protein Insulin from the adipocytes of the Carp, said method comprising steps of reverse transcripting RNA of adipocytes to obtain cDNA, using oligonucleotide primers of SEQ ID Nos. 5 and 6 to identify AdpInsl gene from cDNA, and deducing amino acid sequence from cDNA to obtain protein Insulin, and an adipocyte of Catla useful for producing the said Insulin.
The scientists involved in the invention are Samir Bhattacharya, Sib Sankar Roy, Subrata Dasgupta and Mohua Mukherjee.