Pfizer announced that new data regarding the cardiovascular and kidney function effects of Lipitor (atorvastatin calcium)
A new post-hoc analysis (planned after the study completed) of the Stroke Prevention by Aggressive Reduction of Cholesterol Levels (SPARCL) study looked at the potential kidney function effects of patients treated with Lipitor 80 mg in post-stroke patients with type 2 diabetes, metabolic syndrome and chronic kidney disease.
A new post-hoc analysis (planned after the study completed) of the Incremental Decreases through Aggressive Lipid Lowering (IDEAL) clinical trial evaluated the effect of Lipitor 80 mg in reducing multiple cardiovascular events in patients with history of heart attack.
"These new analyses will help extend our understanding of Lipitor's impact in patients who have experienced multiple cardiovascular events and also in post-stroke patients with type 2 diabetes, metabolic syndrome and chronic kidney disease. These post-hoc analyses come from two of the more than ten landmark trials studying the benefits of Lipitor on cardiovascular outcomes," said Dr. Rochelle Chaiken, vice president, Cardiovascular and Metabolic Medical Division, Pfizer.
Lipitor is the only statin proven to provide a combination of impressive average LDL lowering of 39 to 60 per cent, significant and proven cardiovascular event reductions, and a well-established safety profile across a broad range of patients.
It is the most prescribed cholesterol-lowering therapy in the world, with nearly 144 million patient-years of experience. Lipitor is supported by an extensive clinical trial program involving more than 400 ongoing and completed trials with more than 80,000 patients.
Lipitor is a prescription medication. It is used in patients with multiple risk factors for heart disease such as family history, high blood pressure, age, low HDL ("good" cholesterol) or smoking to reduce the risk of a heart attack and stroke, certain kinds of heart surgery and chest pain.
Lipitor is also used in patients with type 2 diabetes and at least one other risk factor for heart disease such as high blood pressure, smoking or complications of diabetes, including eye disease and protein in urine, to reduce the risk of heart attack and stroke. It is used in patients with existing coronary heart disease to reduce the risk of heart attack, stroke, certain kinds of heart surgery, hospitalisation for heart failure, and chest pain. When diet and exercise alone are not enough, Lipitor is used along with a low-fat diet and exercise to lower cholesterol.