Eurocor GmbH, a wholly-owned subsidiary of Opto Circuits (India) Ltd. has submitted the 12 months outcome of patients study registered at the Spanish Multicentre Registry during the international symposium held at Paris recently.
There were 250 patients enrolled at 10 Spanish centres. The study was conducted to investigate the outcome after Dior drug-eluting balloon (DEB) was used for the treatment of in-stent restenosis (ISR) lesions.
The investigations included ISR due to bare metal stents (BMS) as well as ISR due to drug-eluting stents (DES). A second focus of that study was the treatment of small vessels, on a challenging subset of patients, where treatment options are currently limited. The results at 12 months follow-up show a low target lesion revascularization (TLR) rate of 9.2 per cent in BMS-ISR and 14.8 per cent in DES-ISR. In very small vessels (1.98 mm mean vessel diameter) the TLR rate at 12 months was very low with 2.9 per cent, which is remarkable. The treatment of coronary in-stent restenosis with the paclitaxel-eluting balloon Dior provides good immediate and midterm outcomes. The manuscript on the subset of patients with ISR lesions has been accepted for publication recently. The results were presented by Dr Antonio Serra of Spain.
During the Paris symposium, Prof Silber from Germany pointed out that the Dior DEB was in accordance with the ESC guidelines, 2010 IIa, which recommends that DEB can be used for ISR in BMS.
Dr Pieter Stella from Netherlands then presented the database of the Valentines Trial with the largest group of patients ever enrolled to show efficacy of DEB in treatment of ISR. The studies show that the Dior DEB is safe and effective in ISR.
Prof Schulte from Germany provided a glimpse of first experiences with the drug-eluting peripheral PTA Balloon Freeway and announced the first results of a new randomized study. Dr Chandra from India, Dr Alfredo Rodriguez from Argentina and Prof Huay Cheem Tan from Singapore rounded off the session with an international view on innovative DEB technologies and experiences with high class products such as Dior and Freeway.