CardioTech International announced the award of US patent no. 6,117,535 "Biocompatible Devices". The patent discloses a unique method of reinforcing vascular grafts with polyurethane monofilaments that result in compliant, elastic and torque-resistant grafts.
The invention is based on the properties of ChronoFlex biodurable polycarbonate-based polyurethane elastomers. ChronoFlex filaments are inherently elastic, thus producing elastic small bore vascular grafts, compared to standard ePTFE grafts that are stiff and non-compliant.
The use of ChronoFlex monofilaments as reinforcement produce elastic and torque-resistant small-bore vascular grafts. The filaments, 250 microns in diameter, are automatically applied onto the outer surface of pre-formed microporous vascular grafts by a precision machine, which applies a mist of solvent onto the monofilaments turning them temporarily adhesive.
Once adhered onto the surface, the monofilaments can remain permanently attached, or may be manually removed during use without damaging the structural integrity of the microporous graft.
Dr. Michael Szycher, senior inventor stated: " This is a technical breakthrough in our quest for a synthetic substitute for human saphenous veins.