Waters has partnered with Ohio State University’s Campus Chemical Instrument Centre and recognized its efforts in understanding of conditions like high blood pressure, arteriosclerosis, pre-eclampsia, and chronic obstructive pulmonary disease, among others.
The Centre is headed by Prof. Vicki Wysocki, professor of chemistry and biochemistry. The facility is widely renowned for fundamental research on characterizing protein complexes, or assemblies of multiple individual proteins, that living organisms depend on for their survival.
“We are honoured to join the Waters Centers of Innovation Programme as a partner and applaud the state-of-the-art instrumentation and technical support that Waters has provided,” said Caroline Whitacre, vice president for research, Ohio State University Laboratory.
“Having access to the Waters technology has enabled to develop improved mass spectrometry approaches to determine structures of protein complexes. This research is helping researchers across the Ohio State campus and elsewhere to achieve breakthroughs and develop solutions that will have global impact,” she added.
“One of the important goals of our research is understanding how we might interrupt a disease or correct for a disease, or develop a drug target. Waters instruments are important to our research because of the ion mobility technology embedded in their quadrupole time-of-flight mass spectrometers. This technology allows us to measure not just a protein complex’s mass/charge ratio,” said Wysocki.
The driving force behind the technique of surface induced dissociation (SID) for mass spectrometry, Prof. Wysocki leads a research group exploring new ways of examining protein complexes.
In recognition of Prof. Wysocki efforts, Waters sponsored a symposium recently on 'Mass Spectrometry in Structural Biology' at the Ohio State University campus. Invited lectures at the symposium included Prof. David Russell, Texas A&M Prof. Joseph Loo, UCLA; Prof. Evan Williams, UC Berkeley; Prof. Lisa Jones, IUPUI; Prof. Perdita Barran, University of Manchester (UK); Prof. David Clemmer, Indiana University; and Kevin Giles, Waters Corporation.