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DBT & STEM CELL RESEARCH
JOE C MATHEW | Wednesday, September 28, 2005, 08:00 Hrs  [IST]

The capability of Department of Biotechnology (DBT) to develop a niche area through sector specific, time bound R&D programmes was first recognized when it announced its achievements in bioinformatics sector. The countrywide bio-grid network DBT was instrumental in setting up has taken India a long way in the specific discipline. It is heartening to know that DBT has taken a similar interest in the area of stem cell research. Major initiatives have been taken to develop stem cell research programmes for limbal, haematopoitic, neural, liver, cardiac, embryonic and human corneal stem cells and the stem cell preservation. Limbal stem cells are being used at L.V. Prasad Eye Institute (LVPEI), Hyderabad, to repair cornea surface disorders caused by limbal stem cells deficiencies. Under the programme supported at Christian Medical College (CMC), Vellore, a technology has been established for collection, purification and haplo-identical haematopoietic stem cell transplantation. The studies conducted at the National Centre for Cell Science (NCCS), Pune and the Indian Institute of Science (IISc.), Bangalore, showed that banana lectins have stem cell preservation activities. Long and short term training programme have been initiated. National and International conferences on the various aspects of the subject are being periodically organized. Inter institutional city clusters programmes have been implemented at Vellore and Pune by involving basic researchers, clinicians and industry. This includes sharing of information, exploration of collaboration and discussion on emerging policy issues etc. Bangalore, Hyderabad and Delhi city cluster programmes are being considered. It is also proposed to establish Centres of Excellence for stem cell research initially at 2 or 3 places to initiate focused, targeted programmes on human stem cell research by involving basic researchers and clinicians.

Considering the fact that stem cell research world over is still in its infancy, DBT's attempt should be lauded. It has rightly initiated brainstorming meetings on stem cells to identify the priorities and to examine the possibilities to enhance research in this area in the country. The main features of strategy include promotion of stem cell research for therapeutic applications using adult and embryonic stem cells as well as other more readily available sources such as bone marrow, peripheral blood and umbilical cord blood cells. In order to give legislative support to its initiatives and to ensure uninterrupted flow of funds for the R&D programmes, a National Biotech Strategy is also being prepared. The policy, which is being framed after due consultations with senior scientists, policy makers, representatives of the industry, NGOs and other stakeholders, is meant to promote biotechnology innovation, research and product development to facilitate economic growth. In the words of Kapil Sibal, Minister for Science and Technology, "the strategy is being formulated to ensure that the country not only builds on the existing platform but expands the base to create global leadership in biotechnology by unleashing the full potential that the country has to offer". Let's wish him the best.

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