Certara, a leading provider of software and scientific consulting services to improve productivity and decision-making from drug discovery through drug development, has partnered with LabLogic Systems to integrate Certara’s Phoenix WinNonlin pharmacokinetic (PK)/pharmacodynamic (PD) modelling and non-compartmental analysis product with LabLogic’s Debra Laboratory Information Management System (LIMS).

Debra is used to manage data from absorption, distribution, metabolism, and excretion (ADME) and protein-binding studies. The resulting solution, allows customers who are using Debra 6 as their LIMS for drug metabolism studies, to push their data directly into Phoenix WinNonlin.

“This integration will allow the two systems to communicate directly, thus removing the need to export data from Debra,” said Dr Daniel Weiner, senior vice president and general manager at Certara. “It will increase system usability and should also provide quality control benefits.”

Debra can manage mass balance, tissue distribution, and PK results from ADME studies. With the addition of LabLogic’s Protein Binding module, Debra can also perform a comprehensive series of protein-binding assays.

Phoenix WinNonlin provides robust, intuitive modelling tools that allow researchers to visualize and analyze their PK and PK/PD data easily. It also enables them to collect all their results, including plots, tables and workflows, in a single project file. This convenient data management approach encourages results sharing and collaboration between team members.

“We developed this integration for Debra and Phoenix WinNonlin, two industry standard drug discovery software products, in direct response to customer requests,” said Huw Loaring, systems director at LabLogic. “We are always looking for ways to help our pharmaceutical customers to streamline their drug discovery process.”

LabLogic is managing customer requests for this product integration.

Certara is dedicated to improving human health by delivering a broad spectrum of software products and consulting services, spanning molecular discovery to clinical development, with special focus on supporting translational approaches to drug development.

LabLogic Systems is a premier instrument and software provider supporting PET/nuclear medicine facilities, pharmaceutical companies, agrochemical research, universities and contract research organizations for over 30 years.