Clinical Laserthermia SystemsAB (CLS) (publ) and Exact Imaging have signed a memorandum of understanding (MoU) to enter into a commercial collaboration to jointly optimize a product for high resolution micro-ultrasound guided focused laser ablation (FLA).  The goal is to offer the urologic market a superior solution for image guided focal therapy in patients with localized prostate cancer and BPH.

CLS markets and sells Tranberg | Thermal Therapy System for image guided FLA in the US and European markets. Image guided means that the physician uses magnetic resonance images (MRI) or ultrasound images, for example, to identify targets, guide placement of instruments, and for monitoring of the FLA treatment. Exact Imaging is the world’s leader in high resolution micro-ultrasound systems, enabling real-time imaging and biopsy guidance for the prostate. Its ExactVuplatform is today used primarily for image guidance during targeted prostate biopsy procedures.

"The intended collaboration will strengthen both companies' product offerings, expand the addressable market, and further increase focus on sales. Ultrasound equipment is available today at most hospitals. However, we believe the 29 MHz ExactVu system, Exact Imaging's micro-ultrasound platform, dramatically increases the user’s ability to see diseased tissue, to correctly place CLS instruments and most importantly, to better monitor the FLA treatment itself. The intention is to offer the urologic market the safest, most complete, and cost effective solution for focal therapy of prostate cancer and BPH," says Dan Mogren, CCO at CLS.

CLS and Exact Imaging have signed the MoU with the aim of entering into a commercial collaboration during 2018, where the parties will market and sell a jointly optimized product for micro-ultrasound guided FLA treatment in prostate.

CLS estimates that the total addressable market (USA / EU / Japan) for image guided focal therapy of benign prostatic hyperplasia (BPH) and localized prostate cancer amounts to approximately 500,000 treatments per year. CLS products are currently included in a clinical study at Toronto General Hospital in Toronto, Canada. The study investigates image guided FLA of localized prostate cancer and is being conducted at the hospital's initiative and comprises 25 patients.

Exact Imaging is the world’s leader in high-resolution micro-ultrasound systems enabling real-time imaging and guided biopsies in the urological market for prostate cancer.

Clinical Laserthermia Systems AB (publ), develops and sells the Tranberg|Thermal Therapy System including its specially-designed sterile disposable products for safe, gentle and effective treatment of soft tissue such as cancerous tumors.