Swiss-based research informatics provider Genedata announced its collaboration with Tokyo Medical University, AMR Inc., and Leica Microsystems in a proteomics research initiative aiming at the identification of metastatic biomarkers for the discovery and validation of new protein drug targets.

In the project, proteins extracted from lung and endocrine carcinoma FFPE tissue collections are analyzed using state-of-the-art MS-based proteomic methodologies. Formalin-fixed and paraffin-embedded (FFPE) tissue samples have been extensively collected and annotated in hospitals around the globe representing an invaluable resource to study the progression of diseases in detail.

For the downstream molecular analysis, Genedata provides Expressionist, its modular enterprise system for biomarker discovery, along with comprehensive professional services. The high-throughput capabilities for quality assessment, pre-processing and integrated analysis make Genedata Expressionist a superior choice to handle the breadth and complexity of the mass-spectrometry based proteomics data, leading to the detection of molecular effects and interactions that would have otherwise gone unnoticed.

"Genedata`s support for our proteomics 'star alliance' is proving to be of outstanding value. Genedata Expressionist, as a capable high-throughput solution for proteomics analysis, is the key to unlocking a treasure chest of clinical samples for metastatic biomarker research that were intractable before," said Professor Toshihide Nishimura, Department of Surgery, Tokyo Medical University, and Senior Advisor, Expression Pathology Inc. (USA)

"We are very pleased with our unique contribution," said Dr. Frank Staubli, representative director, Genedata KK. "MS-based retrospective proteomics represents an opportunity as well as a challenge for an integrated data processing and analysis system. Genedata Expressionist`s performance exceeds our expectations, and shows great potential for the scope of the collaboration."

Genedata specializes in discovery informatics for biotech, pharmaceuticals and the life sciences. The company offers expertise in research informatics combined with open and scalable computational solutions. The companies' solutions include Genedata Phylosopher for integrating, structuring, and analyzing research data; Genedata Screener for high throughput screening analysis; and Genedata Expressionist for omics data integration, processing and analysis.