Norgine B.V.’s partner Arc Medical Design Ltd. announced that the device Endocuff can significantly improve overall colonoscopy performance by Making the colonoscopy quicker Caecal intubation time (CIT) – 22.36%,p<0.005;  Increasing Adenoma Detection Rate (ADR) – 13.8%,p<0.05 and Increasing Mean number of adenomas per procedure (MAP) - 83%,p<0.05.

This prospective observational study was presented at Digestive Disease Week 2015.

Endocuff is a simple device attached at the end of the colonoscope that opens up the field of view by retracting folds during withdrawal.

The study was divided in three consecutive periods: pre-cuff (no device used), during-cuff (device used) and post-cuff (no device used). Key quality colonoscopy indicators used were Adenoma Detection Rate, Mean number of adenomas per procedure and Caecal intubation time with a total number of procedures performed was 399.

Peter Martin, COO at Norgine said: “Improving quality of endoscopy is important because effective colon cancer screening lowers colon cancer rates and mortality. Endocuff can transform patient’s care because it clearly improves diagnosis  of lesions but also delivers better quality colonoscopy.”

Tas Javed, MD at Arc Medical said: “ Endocuff is already available for use in the US and in Europe and we are confident that extensive use of the device when performing colonoscopy will help save lives and has the potential to ultimately reduce healthcare bills.”

Colorectal cancer is the second most common cause of cancer-related mortality in the world, with 412,00 new diagnoses every year in Europe.

Endocuff Vision is a single-use endoscopic overtube, which fits onto the distal end of an endoscope. The size of the device is approximately 2.5cm long by 1.5cm wide (3.5cm with arms extended), and is of minimal weight.

Endocuff Vision has unique hinged arms that lie flat against the shaft of the endoscope to create a smooth, low friction surface during intubation. During extubation the arms of the device flare out to stabilise the tip of the endoscope and centre it in the lumen, providing greater control and enabling the physician to flatten the folds of the colon, leading to superior visualisation.

The device is manufactured in the UK by Boddingtons Plastics Limited, a plastics manufacturer, which currently holds the CE mark for the product.

Norgine is a European specialist pharmaceutical company that has been established for over 100 years. In 2014, Norgine’s total revenue was €296 million and the company employs over 1,000 people.