Open Monoclonal Technology, Inc. (OMT), a leader in genetic  engineering of animals for discovery of human therapeutic antibodies, naturally optimized human antibodies, has granted unlimited OmniRat, OmniMouse and OmniFlic access to a global leader in generics and novel pharmaceuticals.  


Under the agreement, the pharmaceutical company will be able to generate human monoclonal and bispecific antibodies against any target for any indication globally. The company will pay an upfront and annual platform access fees as well as clinical milestones and royalties for each successful product.

Dr. Roland Buelow, founder and CEO of OMT, said “OMT has made its therapeutic human antibody platforms available to the industry’s leading pharmaceutical, biotech, health care and R&D service companies. This new partnership is with one of the world’s largest generics and ethical drug companies that will be able to leverage their geographical reach and commercial strength to take full advantage OMT’s human antibody platforms."

OmniRat is the industry’s first human monoclonal antibody technology based on rats. OMT, in collaboration with Pfizer, has shown that OmniRat has a complete immune system with a diverse antibody repertoire and generates antibodies with human idiotypes as well as a wild-type animals make rat antibodies.

OmniMouse is a transgenic mouse that complements OmniRat and expands epitope coverage. Both deliver human antibodies with high affinity, specificity, expression, solubility and stability.

OmniFlic is the first engineered rat with a fixed light chain for discovery of bispecific, fully human antibodies.