Phalanx Biotech Group, a global provider of genomic products and services, launches a major update to its OneArray microRNA expression profiling microarrays based on the latest miRBase release – Version 17. This miRBase release represents a significant increase over Version 16 in the number of microRNA sequences with 2,406 additional mature microRNA - of which 563 represent newly verified sequences in human, mouse and rats.
Researchers using OneArray microRNA products will benefit from more comprehensive interrogation power of validated microRNA transcripts as opposed to those using Affymetrix, Agilent or Exiqon microarrays based on older miRBase versions. The OneArray microRNA line includes human, mouse, rat and seven major plant species - rice, corn, soybean, grapevine, Sorghum, Arabidopsis, and Brachypodium.
“At Phalanx Biotech, we continuously strive to make improvements in probe coverage, performance, and usability for all of our OneArray microarray products. This latest microRNA product release marks the third update to our microRNA product line, and features not only the most current annotation, but also a new hybridization chemistry enabling greater microarray signal intensities at reduced sample input,” said Richard Su, Head of Product Development. “Furthermore, as our whole genome gene expression microarray product line expands, we anticipate a set of complementary microRNA microarrays to offer researchers the capability to conduct gene and microRNA expression profiling studies in parallel.”
The OneArray product line consists of microarrays for whole genome gene and microRNA expression profiling. As a complement to the Rice OneArray, the Plant microRNA OneArray incorporates major crops including rice, wheat, corn, sorghum, and grape. All arrays conform to the strictest quality control standards and are manufactured using proprietary PhalanxJet spotting technology, specialized coating chemistry, and a fully automated assembly system. Phalanx Biotech’s unparalleled expertise in microarray technologies forms the basis for an exceptional OneArray Service Team dedicated to offering genomic research solutions from sample preparation to data analysis.
MicroRNA or miRNA are short ribonucleic acid molecules (approximately 22 nucleotides long) that often play roles in regulating the expression of genes, usually by binding to target messenger RNA (mRNA) sequences and impeding their function through mRNA degradation or blocking the translation of mRNA. Researchers are focusing their efforts in uncovering the regulatory circuitry afforded by microRNA – investigating the role of microRNA in processes as diverse as embryonic development, cell proliferation, differentiation, and apoptosis. Comparative microRNA expression profiling studies among different cell populations and tissue types demonstrate increasing correlations between microRNA and disease. The combination of gene expression and microRNA profiles will enhance our understanding of biological mechanisms and the genes associated in these processes.
Phalanx Biotech Group, provides genomics research products and services worldwide to academic, pharmaceutical and biotech communities.