Stem Cell Sciences plc, (SCS) a company focused on the commercialisation of stem cells and stem cell technologies, has licensed IRES technology to a leading provider of genetically modified rat and mouse models for medical and pharmaceutical research.

Under the terms of the multi-year agreement, which is non-exclusive and retroactive, the undisclosed partner will gain access to the IRES technology for use in its own research and development activities. Under the terms of the licence, SCS will receive US$750,000 over six years plus royalties.

SCS' IRES (Internal Ribosome Entry Site) technology enables researchers to monitor the activity of a particular gene of interest in living cells or tissues without blocking the normal function of the gene. In particular, IRES is important for evaluating the success of gene knock-outs or knock-ins in stem cells, which is crucial for the successful creation of transgenic mouse and rat disease models.

Dr Alastair Riddell, CEO of SCS, said "A key element of our commercial strategy is to realise both immediate and longer-term value from our extensive IP portfolio in the stem cell field through licence agreements such as this. We are therefore very pleased to have signed this agreement with one of the leading providers of transgenic animal models to the pharmaceutical research industry. We are continuing discussions with other companies, which may benefit from the use of SCS technology in conjunction with their own, and are optimistic of signing further agreements in the coming months."

Stem Cell Sciences (SCS) is an international research and development company focusing on the commercial application of stem cell biology technologies for drug discovery and regenerative medicine research. Stem Cell Sciences is now focussing on building revenues through the sale of products, collaborative research and licensing deals with international biotechnology and pharmaceutical companies.