The US Food and Drug Administration (FDA) advised health care practitioners and patients against using certain glucose monitoring technology that employs a specific test strip when the patients are also receiving therapeutic products containing non-glucose sugars.

Non-glucose sugars contained in some therapeutic products such as peritoneal dialysis solutions and certain immunoglobulins can falsely elevate glucose results, which may prompt excessive insulin administration. These therapeutic products, which are labelled to indicate that they may interfere with this particular glucose monitoring technology, are mostly used in patients with serious medical conditions, including kidney failure and moderate to severe rheumatoid arthritis.

In a Public Health Notification and an accompanying Advice for Patients, the FDA listed the manufacturers and brands of glucose test strips that contain glucose dehydrogenase pyrroloquinoline quinone (GDH-PQQ)-the chemical that reacts with the non-glucose sugars (maltose, galactose and xylose) contained in some therapeutic products that produce a falsely high test result,

Most GDH-PQQ devices are used in health care facilities, which should instead use a laboratory assay to measure a patient's glucose if the patient is also receiving an interfering product. The FDA also makes recommendations to minimize the risk of potential shortages of these products until health care facilities can obtain non-GDH-PQQ strips and meters.