In a bid to offer the advantages of advanced technology, Waters Corporation has teamed-up with leading international science labs and bioinformatics companies to increase its product efficiency and also help users to economize cost and time in research.

Five new initiatives were announced at the 55th American Society of Mass Spectrometry (ASMS) Conference, held between June 3 to 7, Indianapolis IN.

As a first step, Waters in collaboration with leading biopharmaceutical researchers is developing BiopharmaLynx Application manager software. The product gives scientists the ability to automatically calculate the percentage of protein variant and determine the biopharmaceutical identity, purity, stability levels both accurately and precisely.

In association with Dotmatics, a scientific software company, Waters will develop an integrated advanced structure elucidation software to complement its time-of-flight (Tof) mass spectrometers and the Waters Synapt and MALDI Synapt High Definition Mass Spectrometry (HDMS) Systems. The new software will give scientists the ability to comprehensively identify ion fragments by accurately interrogating small molecule MS/MS, or MS E, data for discovery, development, and manufacturing analyses in the chemical and pharmaceutical industries, said Dr Tim Riley, vice-president and managing director, Pharmaceutical Business Operations, Waters.

The third new product is a comprehensive peptide ion accounting informatics which can mine deeper into UPLC/MS data to identify more peptides/proteins with greater sequence coverage and statistical rigor than conventional LC/MS/MS methods. The system solution is fully supported with quality control standards, defined methods, training and support to ensure reproducible operation and consistent results.

Another novel addition in the area of advanced biological research is the High Definition Mass Spectrometry (HDMS) systems, a dual ionization mass spectrometer featuring both MALDI and atmospheric pressure ionization (API) capability as standard features giving scientists maximum analytical power for discovery research challenges. The system is operable in both time-of-flight (Tof) mode for exact mass UPLC/MS/MS experiments, and ion-mobility/Tof mode for performing novel ion mobility separations-based investigations. The system also features TriWave technology capable of performing "time aligned parallel" (TAP) fragmentation.

"This breakthrough in MALDI technology demonstrates our commitment to leadership in high-end mass spectrometry. We believe that the MALDI Synapt HDMS system will become the platform of choice in a number of disciplines - from metabolite identification and profiling, structural biology, biomarker discovery and molecular imaging, through to ground-breaking experimentation in which our customers can exploit the new dimension of ion mobility separation to take their research in entirely new directions," stated Dr Tim Riley.

The fifth development at Waters is the publication of a book titled 'Beginners Guide to Liquid Chromatography'. The 56-page paperback focuses on high-performance liquid chromatography (HPLC) and offers lucid presentation of the technology with colorful diagrams to acquaint the reader with basic concepts and terminology. No previous scientific training is required to obtain a better working knowledge of this powerful technology.

Waters Corporation creates business advantage for laboratory-dependent organizations by delivering practical and sustainable innovation to enable significant advancements in such areas as healthcare delivery, environmental management, food safety, and water quality worldwide. The company has pioneered in separations science, laboratory information management, mass spectrometry and thermal analysis. In 2006, Waters clocked revenue of $1.28 billion and has a strength of 4,700 employees.